BDBM50064171 1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexahydropyridine)]::1'-benzylspiro[chroman-2,4'-piperidine]::CHEMBL38634

SMILES C(N1CCC2(CC1)CCc1ccccc1O2)c1ccccc1

InChI Key InChIKey=CRKWADRIYCMTBU-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50064171   

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi:  0.617nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in human Jurkat cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi:  0.620nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed